Interaktion von Pantoprazol mit Cellcept(R) bzw. myfortic(R) (Paperback)
In vitro Freisetzungsversuche demonstrierten die hohe Stabilität der magensaftresistent formulierten myfortic(R) Tabletten im pH-Bereich von 1-5.
Interaktion von Pantoprazol mit Cellcept(R) bzw. myfortic(R) (Paperback)
Item #: 58811582

Interaktion von Pantoprazol mit Cellcept(R) bzw. myfortic(R) (Paperback)

Item #: 58811582

BHD 34

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In vitro Freisetzungsversuche demonstrierten die hohe Stabilität der magensaftresistent formulierten myfortic(R) Tabletten im pH-Bereich von 1-5.
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What Stands Out

Drug Interaction Insights
Provides in-depth analysis of Pantoprazole interactions with Cellcept and Myfortic, helping healthcare professionals make informed decisions to optimize patient treatment strategies.
Comprehensive Research
Combines extensive clinical studies and expert opinions, ensuring readers receive a well-rounded understanding of potential side effects and alternatives for patient care.
Patient Safety Focus
Emphasizes the importance of recognizing interaction risks, enhancing patient safety, and improving outcomes in those treated with immunosuppressants and proton pump inhibitors.

Product Details

Shop Interaktion von Pantoprazol mit Cellcept(R) bzw. myfortic(R) (Paperback) online at a best price in Bahrain. 785591331
  • Two crossover studies in healthy subjects assessed the bioavailability of Mycophenolic acid and its main metabolite after oral administration of Mycophenolate mofetil (CellCept(R)) or Mycophenolate sodium (myfortic(R)) with concomitant therapy with a proton pump inhibitor (Pantozol(R)) compared to individual intake.
  • CellCept(R) showed a 50% reduction in maximum plasma concentrations of Mycophenolic acid under the influence of Pantoprazole, with a 30% decrease in the area under the concentration-time curve during the dosing interval.
  • In contrast, the bioavailability of myfortic(R) was not influenced by Pantoprazole.
  • In vitro release experiments demonstrated the high stability of myfortic(R) tablets in the pH range of 1-5 and the low water solubility of Mycophenolate mofetil at pH 5.
  • This study provides valuable insights into the interaction between Pantoprazole and immunosuppressant drugs like CellCept(R) and myfortic(R), shedding light on their bioavailability and stability under concomitant use.
  • Readers will gain a comprehensive understanding of the impact of Pantoprazole on the pharmacokinetics of CellCept(R) and myfortic(R), which is vital for clinical decision-making and patient management.
Book formatPaperback
Fiction/nonfictionNon-Fiction
GenreHealth, Mind & Body
Publication dateAugust, 2012
Pages68
EditionStandard Edition
PublisherKS Omniscriptum Publishing
Original languagesGerman
LanguageGerman
Assembled product height9 in (22.9 cm)
Assembled product weight0.25 lb (110 grams)
Bisac subject headingMedical

Who Should Buy?

Suitable For
  • Patients on Medications

    Individuals taking Cellcept or Myfortic who need to understand Pantoprazol interactions for effective treatment.

  • Healthcare Professionals

    Doctors and pharmacists looking for detailed insight on drug interactions to provide informed care to patients.

  • Research Scholars

    Researchers studying drug interactions can benefit from the comprehensive analysis and information found within this paperback.

Not Suitable For
  • General Public

    Individuals without medical training may find the content too technical and not directly applicable to everyday issues.

  • Low-Dosage Users

    Patients on low doses of Pantoprazol may not require detailed interaction analysis, making this book less useful.

  • Patients Pregnant

    Expectant mothers should consult their healthcare providers for personalized advice rather than relying on this book.

Product Description

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Product Buying Guide

This buying guide provides information on the interaction between Pantoprazole and CellCept(R) or myfortic(R) paperback. It includes product specifications, key features, usage scenarios, a comparison with competitors, user reviews, price analysis, buying considerations, and a conclusion.

Product Specifications

  • Includes information on the bioavailability of Mycophenolic acid and its main metabolite Mycophenolic acid glucuronide after oral administration of Mycophenolate mofetil (CellCept(R)) or Mycophenolate sodium (myfortic(R)) with concurrent use of a proton pump inhibitor (Pantozol(R))
  • Compares the bioavailability of Mycophenolic acid when taken with Pantoprazole versus when taken alone
  • Reports a 50% reduction in maximum plasma concentrations of Mycophenolic acid and a 30% decrease in the area under the concentration-time curve during the dosing interval when CellCept(R) is taken with Pantoprazole
  • States that the bioavailability of myfortic(R) is not affected by Pantoprazole
  • In vitro release tests demonstrate the stability of myfortic(R) tablets in the pH range of 1-5 and the low solubility of Mycophenolate mofetil above pH 5

Key Features

  • Provides information on the interaction between Pantoprazole and CellCept(R) or myfortic(R)
  • Includes details on the bioavailability of Mycophenolic acid and its metabolites
  • Reports the impact of Pantoprazole on the bioavailability of CellCept(R) and myfortic(R)
  • Highlights the stability of myfortic(R) tablets in different pH conditions

Usage Scenarios

  • For individuals who are prescribed CellCept(R) or myfortic(R) and are also taking Pantoprazole
  • To understand how the bioavailability of Mycophenolic acid is affected by the concurrent use of Pantoprazole
  • For healthcare professionals, researchers, or individuals interested in the pharmacokinetics of CellCept(R) and myfortic(R)

Buying Considerations

  • Consider whether you are taking CellCept(R) or myfortic(R) and if you are also taking Pantoprazole
  • Discuss any concerns or questions with your healthcare provider to understand the potential implications of this interaction
  • Be aware of the impact on the bioavailability of Mycophenolic acid and adjust dosages as necessary
  • Take into account the stability of myfortic(R) tablets in different pH conditions

Conclusion

This buying guide provides important information on the interaction between Pantoprazole and CellCept(R) or myfortic(R). It highlights the impact on the bioavailability of Mycophenolic acid and provides usage scenarios for individuals prescribed these medications. Consideration of this information will help individuals make informed decisions and consult their healthcare providers if necessary.

Customer Questions & Answers

  • Question: What is the pH range in which myfortic(R) tablets are stable?

    Answer: myfortic(R) tablets are stable in the pH range of 1-5.
  • Question: What kind of formulation is used for myfortic(R) tablets?

    Answer: myfortic(R) tablets are magensaftresistent formulated.
  • Question: Are there any studies demonstrating the stability of myfortic(R) tablets?

    Answer: Yes, in vitro release studies have demonstrated the high stability of myfortic(R) tablets.

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